Drese to make Nats' debut

Drese set for a new beginning

The Nationals will try to start another winning streak Wednesday. If they do, they'll also win their Interleague series against the American League West-leading Angels.

Ryan Drese will make his first start as a National. He should be well-rested, not having pitched since a 2 2/3-inning outing June 7. The right-hander is a solid 4-3 with a 4.19 ERA in seven career starts against the Angels.

The Angels will counter with former Expo Bartolo Colon. Colon, who was 10-4 with a 3.31 ERA for the Nationals in 2002, is 4-0 over his last six starts.

Washington trailed Tuesday, 3-1, but Jose Guillen's two-run homer sparked a four-run rally in the eighth and the Nationals held on for a 6-3 win.

Pitching matchup
WAS: RHP Ryan Drese
• 4-6, 6.46 ERA in 2005
• 0-1, 3.86 ERA vs. LAA in 2005

LAA: RHP Bartolo Colon
• 8-3, 3.09 ERA in 2005
• Has not faced WAS in 2004 or 2005

Players to watch
Nick Johnson is 3-for-4 with a home run and two walks against Colon and has reached base in 61 of his 64 games this season.

"We hold a team to three runs or less, we are right in the ballgame and we usually comeback late in the ballgame and win those ballgames as we did tonight." -- manger Frank Robinson on Tuesday's win

On the Internet
 Gameday Audio
Official game notes

On television

On radio
• WAS: Z104-FM
• LAA: KSPN 710 AM; KTNQ 1020 AM (Español)

Quick hits
Chad Cordero recorded his league-leading 20th save Tuesday, pitching a perfect ninth. ... Wil Cordero recorded his first hit of the season, singling and scoring in the eighth. ... Twenty-seven of the Nationals' 38 wins have been of the come-from-behind variety. ... Guillen is two RBIs shy of 500 in his career.

On deck
• Thursday: Off-day
• Friday: at Rangers, 8:05 p.m. ET
• Saturday: at Rangers, 8:05 p.m. ET

Mark Thoma is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.