Rendon hurt the ankle in the fourth inning after a hitting a double and trying to score on a bloop single to center by Justin Bloxom. The Nationals' No. 2 prospect went down with the ankle injury after rounding third base.
Rendon has had a history of injuries, including shoulder and ankle problems. However, that didn't stop the Nationals from making him their top pick in the 2011 First-Year Player Draft.
In 63 games with Rice University last year, Rendon hit .327 with six home runs, 27 RBIs and an on-base percentage of .520.
Thus far, Rendon has played in two games for Potomac and is 2-for-4 with a run scored.
Bill Ladson is a reporter for MLB.com and writes an MLBlog, All Nats All the time. He also could be found on Twitter @WashingNats. This story was not subject to the approval of Major League Baseball or its clubs.