Rendon hurt the ankle in the fourth inning after a hitting a double and later trying to score on a bloop single to center by Justin Bloxom. The Nationals' No. 2 prospect went down with the ankle injury after rounding third base.
"He is in a boot. He is immobilized. He is going to see a foot and ankle specialist on Friday," Nationals general manager Mike Rizzo said about Rendon. "[The doctors] tell me that his season in not in jeopardy. The slight fracture probably heals quicker and cleaner than a bad sprain."
As for Class A Hagerstown outfielder Brian Goodwin, he suffered a hamstring injury in an 8-7 victory over Lexington on Monday. He, too, has been placed on the 7-day disabled list.
Goodwin was 6-for-16 (.375) with two home runs and eight RBIs this season.
"He should be fine in the next couple of weeks," Rizzo said.