The ball was hit an estimated 431 feet, the second longest hit at Petco Park, according to ESPN's home run tracker.
"The Padres pitched him tough. He hit a heck of a pitch -- a great sinker and he crushed it. It's nice to have him back," manager Davey Johnson said.
Bill Ladson is a reporter for MLB.com and writes an MLBlog, All Nats All the time. He also could be found on Twitter @WashingNats. This story was not subject to the approval of Major League Baseball or its clubs.